Thiol- disulphide levels of 20 patients with ESS at any time compared with 68 patients without ESS.
Euthyroid sick syndrome free#
Free T4 and fT3 levels were significantly low ( P <0.001 for both). Patients with ESS before transplantation had also significantly higher creatinine levels compared to patients without ESS ( P = 0.034). After transplantation, patients with ESS had significantly higher urea and creatinine (respectively, P = 0.025 and P = 0.009), and lower fT4, fT3, total protein, and albumin ( P = <0.001 for all parameters) compared to patients without ESS. Sixteen of 24 (66.7%) patients with ESS before transplantation reached to normal thyroid functions after transplantation. Frequency of ESS was 19.8% in patients followed with ESRD. Of 39 patients, 24 (61%) had ESS before transplantation and 15 (39%) after transplantation. ESS was detected in 39 (32%) of 121 patients. Of these, 69 (57%) were males and 52 (43%) were females. One- hundred twenty one patients were included in the study. ESS was diagnosed in patients with unresponsive TSH to low fT3 and/ or fT4 levels, Thiol and disulphide parameters of patients before and after transplantation were also recorded. In this study, free triiodothyronine (fT3), free thyroxine (fT4) and thyroid stimulating hormone (TSH) levels were recorded before and after renal transplantation in patients with ESRD.
In this study, we aimed to evaluate the frequency of ESS before and after renal transplantation in patients with ESRD, and its association with oxidative stress by evaluating thiol-disulphide levels. ESS can be seen in patients with end stage renal disease (ESRD). Euthyroid Sick Syndrome (ESS) is a thyroid disease appeared in critical and noncritical illnesses.
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